IIR publ. 2003

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2003

Written publications

Books and book chapters:

Østergaard K. Lev godt med slidgigt - ved hjælp af den nyeste forskning og viden. København: Gyldendal; 2003.

Peer-reviewed articles:

Bendtzen K, Bovin LF, Andersen V, Rieneck K, Svenson M. Toll-lignende receptorer. Centrale komponenter i det medfødte immunforsvar og ved overvågning af vævsskade (Review). Tandlægebladet 2003;107:410-5. Abstract.

Bendtzen K, Hansen PR, Rieneck K, The Spironolactone/Arthritis Study Group. Spironolactone inhibits production of proinflammatory cytokines, including tumor necrosis factor a and interferon-g, and has potential in the treatment of arthritis. Clin Exp Immunol 2003;134:151-8. Abstract.

Bendtzen K. Anti-IFN BAb and NAb antibodies: A minireview. Neurology 2003;61, Suppl. 5:S6-S10. Abstract.

Bendtzen K. Immunogenicitet af biologiske lægemidler. Erfaringer med betainterferon, EPO og anti-TNF [Immunogenicity of biopharmaceuticals. Experience with interferon-beta, EPO and anti-TNF](Review). Ugeskr Laeger 2003;48:4629-32. Abstract.

Bendtzen K. Problemer ved klinisk brug af rekombinante proteiner [Problems with clinical use of recombinant proteins] (Editorial). Ugeskr Laeger 2003;48:4625. Editorial as PDF file.

Bergmann OJ, Christiansen M, Laursen I, Bang P, Hansen NE, Ellegaard J, Koch C, Andersen V. Low levels of mannose-binding lectin do not affect occurence of severe infections or duration of fever in acute myeloid leukaemia during remission induction therapy. Eur J Haematol 2003;70:91-7.

Birkeland SA, Hamilton-Dutoit S, Bendtzen K. Long-term follow-up of kidney transplanted patients with posttransplant lymphoproliferative disorder: duration of posttransplant lymphoproliferative disorder-induced operational tolerance, interleukin-18 course, and results of retransplantation. Transplantation 2003;76:153-8. Abstract.

Di Marco R, Mangano K, Quattrocchi C, Musumeci R, Speciale AM, Papaccio G, Buschard K, Bendtzen K, Nicoletti F. Curative effects of sodium fusidate on the development dinitrobenzene-sulfonic acid (DNB)-induced colitis in rats. Clin Immunol 2003;109:266-71. Abstract.

Kaneko T, Itoh M, Nakamura Y, Iimura A, Hayashi S, Takahashi K, Stivala F, Bendtzen K, Nicoletti F. Proinflammatory effects of exogenously administered interleukin 10 in experimental autoimmune orchitis. Cytokine 2003;22:50-3. Abstract.

Kristensen K, Bonato S, Breindahl M, Esberg B, Farholt S, Madsen HO, Olsen EM, Petersen K, Teilmann G, Garred P. Mannose-binding lectin in respiratory syncytial virus infection. J Pediatr 2003;143:544-6.

Leslie RG, Prodinger WM, Nielsen CH. Complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) cooperate in the binding of hydrolyzed complement factor 3 (C3i) to human B lymphocytes. Eur J Immunol 2003;33:3311-21.

Nersting J, Andersen V, Bendtzen K. Maturation of human dendritic cells by monocyte-conditioned medium is dependent on trace amounts of lipopolysaccharide inducing tumour necrosis factor. Immunol Lett 2003;89:59-65. Abstract.

Nicoletti F, Di Marco R, Papaccio G, Conget I, Gomis R, Bernardini R, Sims JE, Shoenfeld Y, Bendtzen K. Essential pathogenic role of endogenous IL-18 in murine diabetes induced by multiple low doses of streptozotocin. Prevention of hyperglycemia and insulitis by a recombinant IL-18-binding protein: Fc construct. Eur J Immunol 2003;33:2278-86. Abstract.

Pachner A, Bendtzen K, Bertolotto A, Birnbaum G, Cook SD, Cutter G, Deisenhammer F, Finter N, Freedman MS, Giovannoni G, Grossberg SE, Hartung H-P, Heine H, Johnson KP, Kappos L, Kaufman MD, Krementchutzky M, Munschauer F, Oger J, Petkau J, Phillips JT, Polman CH, Racke MK, Reder AT, Richert J, Richert N, Rudick RA, Schellekens H, Simsarian JP, Sorensen PS, Stark GR, Steiner I, Traboulsee A, Vartanian T, Halper J, Claudio T. Anti-IFNb antibodies in IFNb-treated MS patients. Neurology 2003;61, Suppl. 5:S1-S5.

Pedersen N, Mortensen S, Sorensen SB, Pedersen MW, Rieneck K, Bovin LF, Poulsen HS. Transcriptional gene expression profiling of small cell lung cancer cells. Cancer Res 2003;63:1943-53. Abstract.

Pignatti P, Ciapponi L, Galle P, Hansen MB, Massa M, Meazza C, Paonessa G, Novick D, Ciliberto G, Martini A, De Benedetti F. High circulating levels of biologically inactive IL-6/SIL-6 receptor complexes in systemic juvenile idiopathic arthritis: evidence for serum factors interfering with the binding to gp130. Clin Exp Immunol 2003;131:355-63. Abstract.

Skov S, Rieneck K, Bovin LF, Skak K, Tomra S, Michelsen BK, Odum N. Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression. Blood 2003;101:1430-8. Abstract.

Sorensen PS, Ross C, Clemmesen KM, Bendtzen K, Frederiksen JL, Jensen K, Kristensen O, Petersen T, Rasmussen S, Ravnborg M, Stenager E, Koch-Henriksen N, Danish Multiple Sclerosis Study Group. Clinical importance of neutralising antibodies against interferon beta in patients with relapsing-remitting multiple sclerosis. Lancet 2003;362:1184-91. Abstract.

Sorensen PS, Ross C, Clemmesen KM, Bendtzen K, Frederiksen JL, Jensen K, Kristensen O, Petersen T, Rasmussen S, Ravnborg M, Stenager E, Koch-Henriksen N. Antibodies to IFN-beta: the Danish National IFN-beta Project. Neurology 2003;61:S27-S28. Abstract.

Svenson M, Jacobi HH, Bødtger U, Poulsen LK, Rieneck K, Bendtzen K. Vaccination for birch pollen allergy. Induction of affinity-matured or blocking IgG antibodies does not account for the reduced binding of IgE to Bet v 1. Mol Immunol 2003;39:603-12. Abstract.

Veje K, Hyllested KL, Ostergaard K. Topographic and zonal distribution of tenascin in human articular cartilage from femoral heads: normal versus mild and severe osteoarthritis. Osteoarthritis Cartilage 2003;11:217-27. Abstract.

Woetmann A, Brockdorff J, Lovato P, Nielsen M, Leick V, Rieneck K, Svejgaard A, Geisler C, Odum N. Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling. J Biol Chem 2003;278:2787-91. Abstract.



2003		Written publications
Books and book chapters: Østergaard K. Lev godt med slidgigt - ved hjælp af den nyeste forskning og viden. København: Gyldendal; 2003. Peer-reviewed articles: Bendtzen K, Bovin LF, Andersen V, Rieneck K, Svenson M. Toll-lignende receptorer. Centrale komponenter i det medfødte immunforsvar og ved overvågning af vævsskade (Review). Tandlægebladet 2003;107:410-5. Abstract. Bendtzen K, Hansen PR, Rieneck K, The Spironolactone/Arthritis Study Group. Spironolactone inhibits production of proinflammatory cytokines, including tumor necrosis factor a and interferon-g, and has potential in the treatment of arthritis. Clin Exp Immunol 2003;134:151-8. Abstract. Bendtzen K. Anti-IFN BAb and NAb antibodies: A minireview. Neurology 2003;61, Suppl. 5:S6-S10. Abstract. Bendtzen K. Immunogenicitet af biologiske lægemidler. Erfaringer med betainterferon, EPO og anti-TNF [Immunogenicity of biopharmaceuticals. Experience with interferon-beta, EPO and anti-TNF](Review). Ugeskr Laeger 2003;48:4629-32. Abstract. Bendtzen K. Problemer ved klinisk brug af rekombinante proteiner [Problems with clinical use of recombinant proteins] (Editorial). Ugeskr Laeger 2003;48:4625. Editorial as PDF file. Bergmann OJ, Christiansen M, Laursen I, Bang P, Hansen NE, Ellegaard J, Koch C, Andersen V. Low levels of mannose-binding lectin do not affect occurence of severe infections or duration of fever in acute myeloid leukaemia during remission induction therapy. Eur J Haematol 2003;70:91-7. Birkeland SA, Hamilton-Dutoit S, Bendtzen K. Long-term follow-up of kidney transplanted patients with posttransplant lymphoproliferative disorder: duration of posttransplant lymphoproliferative disorder-induced operational tolerance, interleukin-18 course, and results of retransplantation. Transplantation 2003;76:153-8. Abstract. Di Marco R, Mangano K, Quattrocchi C, Musumeci R, Speciale AM, Papaccio G, Buschard K, Bendtzen K, Nicoletti F. Curative effects of sodium fusidate on the development dinitrobenzene-sulfonic acid (DNB)-induced colitis in rats. Clin Immunol 2003;109:266-71. Abstract. Kaneko T, Itoh M, Nakamura Y, Iimura A, Hayashi S, Takahashi K, Stivala F, Bendtzen K, Nicoletti F. Proinflammatory effects of exogenously administered interleukin 10 in experimental autoimmune orchitis. Cytokine 2003;22:50-3. Abstract. Kristensen K, Bonato S, Breindahl M, Esberg B, Farholt S, Madsen HO, Olsen EM, Petersen K, Teilmann G, Garred P. Mannose-binding lectin in respiratory syncytial virus infection. J Pediatr 2003;143:544-6. Leslie RG, Prodinger WM, Nielsen CH. Complement receptors type 1 (CR1, CD35) and 2 (CR2, CD21) cooperate in the binding of hydrolyzed complement factor 3 (C3i) to human B lymphocytes. Eur J Immunol 2003;33:3311-21. Nersting J, Andersen V, Bendtzen K. Maturation of human dendritic cells by monocyte-conditioned medium is dependent on trace amounts of lipopolysaccharide inducing tumour necrosis factor. Immunol Lett 2003;89:59-65. Abstract. Nicoletti F, Di Marco R, Papaccio G, Conget I, Gomis R, Bernardini R, Sims JE, Shoenfeld Y, Bendtzen K. Essential pathogenic role of endogenous IL-18 in murine diabetes induced by multiple low doses of streptozotocin. Prevention of hyperglycemia and insulitis by a recombinant IL-18-binding protein: Fc construct. Eur J Immunol 2003;33:2278-86. Abstract. Pachner A, Bendtzen K, Bertolotto A, Birnbaum G, Cook SD, Cutter G, Deisenhammer F, Finter N, Freedman MS, Giovannoni G, Grossberg SE, Hartung H-P, Heine H, Johnson KP, Kappos L, Kaufman MD, Krementchutzky M, Munschauer F, Oger J, Petkau J, Phillips JT, Polman CH, Racke MK, Reder AT, Richert J, Richert N, Rudick RA, Schellekens H, Simsarian JP, Sorensen PS, Stark GR, Steiner I, Traboulsee A, Vartanian T, Halper J, Claudio T. Anti-IFNb antibodies in IFNb-treated MS patients. Neurology 2003;61, Suppl. 5:S1-S5. Pedersen N, Mortensen S, Sorensen SB, Pedersen MW, Rieneck K, Bovin LF, Poulsen HS. Transcriptional gene expression profiling of small cell lung cancer cells. Cancer Res 2003;63:1943-53. Abstract. Pignatti P, Ciapponi L, Galle P, Hansen MB, Massa M, Meazza C, Paonessa G, Novick D, Ciliberto G, Martini A, De Benedetti F. High circulating levels of biologically inactive IL-6/SIL-6 receptor complexes in systemic juvenile idiopathic arthritis: evidence for serum factors interfering with the binding to gp130. Clin Exp Immunol 2003;131:355-63. Abstract. Skov S, Rieneck K, Bovin LF, Skak K, Tomra S, Michelsen BK, Odum N. Histone deacetylase inhibitors: a new class of immunosuppressors targeting a novel signal pathway essential for CD154 expression. Blood 2003;101:1430-8. Abstract. Sorensen PS, Ross C, Clemmesen KM, Bendtzen K, Frederiksen JL, Jensen K, Kristensen O, Petersen T, Rasmussen S, Ravnborg M, Stenager E, Koch-Henriksen N, Danish Multiple Sclerosis Study Group. Clinical importance of neutralising antibodies against interferon beta in patients with relapsing-remitting multiple sclerosis. Lancet 2003;362:1184-91. Abstract. Sorensen PS, Ross C, Clemmesen KM, Bendtzen K, Frederiksen JL, Jensen K, Kristensen O, Petersen T, Rasmussen S, Ravnborg M, Stenager E, Koch-Henriksen N. Antibodies to IFN-beta: the Danish National IFN-beta Project. Neurology 2003;61:S27-S28. Abstract. Svenson M, Jacobi HH, Bødtger U, Poulsen LK, Rieneck K, Bendtzen K. Vaccination for birch pollen allergy. Induction of affinity-matured or blocking IgG antibodies does not account for the reduced binding of IgE to Bet v 1. Mol Immunol 2003;39:603-12. Abstract. Veje K, Hyllested KL, Ostergaard K. Topographic and zonal distribution of tenascin in human articular cartilage from femoral heads: normal versus mild and severe osteoarthritis. Osteoarthritis Cartilage 2003;11:217-27. Abstract. Woetmann A, Brockdorff J, Lovato P, Nielsen M, Leick V, Rieneck K, Svejgaard A, Geisler C, Odum N. Protein phosphatase 2A (PP2A) regulates interleukin-4-mediated STAT6 signaling. J Biol Chem 2003;278:2787-91. Abstract.