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Overview of Inflammation
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Note that processes studied in IIR are emphasised in all illustrations.
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The human immune system Innate & adaptive immunity Natural regulation
Dendritic cells (1) MØ/T-cell interact. (1) MØ act./deact. (1_4)
B-/T-mast cell interact. (2) Th1/Th2 cells (3+5) Immunoglobulin (5)
Antibody production (5) Infect. virus (6) Infect. bacteria (6)
Chemokines (HIV) (4+6) Cytotoxicity/apoptosis (7) Inflam. bowel dis. (7)
Vasc. Cytotox. (diabetes) (7) Diabetes (IDDM) (7) Rheumatoid arthritis (8)
Vasculitis (sepsis) (8) Fever/acute-phase (9) CK and CK rec. (10)
AutoAb to CK (11) Atherosclerosis (8+12) Osteoarthrosis (12)
Abbreviations used in the illustrations:
B: B lymphocyte Bas: granulocyte - basophilic DC: dendritic cell
E: endothelial cell Eos: granulocyte - eosinophilic Ery: red blood cell
F: fibroblast FGF: fibroblast growth factor ICAM: intercellular adhesion molecule
LDL: low-density lipid LGL: large granular lymphocyte Mon: monocyte
MØ: macrophage Neu: granulocyte - neutrophil NK: natural killer cell
P: plasma cell ROI: reactive oxygen intermediates RNI: reactive nitrogen intermediates
sLe: sialyl-Lewis blood type components SM: smooth muscle cell T: T-lymphocyte
TGF: transforming growth factor
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